Moderate illness is defined as admitted to an intensive care unit but without use of above organ support measures. Severe illness is defined as a composite indicator of invasive ventilation, use of vasopressor(s)/inotrope(s), and/or use of extracorporeal membrane oxygenation. Main figure presents percentage per age bracket who developed acute kidney injury (AKI) among all hospitalized patients and further stratified by severity of illness status. Age Distribution of Hospitalized Patients with SARS-CoV2 who Experienced AKI within First 7 days of Hospitalization-baseline creatinine estimator FAS equation. Abbreviations: AKI = acute kidney injury, CKD = chronic kidney disease, eGFR = estimated glomerular filtration rate, FAS = full age spectrum, KDIGO=Kidney Disease Improving Global Outcomes, MDRD = modification of diet in renal disease.Īdditional file 3: Supplementary Fig. 2. Yellow line uses the original definition but uses the MDRD equation minus the race variable. Gray line uses the KDIGO guidelines but back calculates the baseline creatinine for all participants using the FAS equation. Orange line assumes that the minimum creatinine during the first 7 days of hospitalization is the baseline creatinine for all participants. The original AKI definition (blue) assumes a baseline creatinine based on KDIGO guidelines for adults (eGFR 75 ml/min/1.73m 2 and back calculates using MDRD equation) and common pediatric definitions assuming an eGFR of 120 ml/min/1.73m 2 and back calculating using height-independent equation, except for patients with CKD when minimum serum creatinine during first 7 days of hospitalization is assumed to be their baseline creatinine value. Main figure presents percentage per age bracket who developed acute kidney injury (AKI) among all hospitalized patients. Age Distribution of Hospitalized Patients with SARS-CoV2 who Experienced AKI within First 7 days of Hospitalization-different baseline creatinine estimators. The Creative Commons Public Domain Dedication waiver ( ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.Īdditional file 2: Supplementary Fig. 1.
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